Toute l’actualité d’OTR3
Latest Publications | Lungs/Poumons | Media Publications | On-going research
Hanan Osman-Ponchet (1) , Laurie Perdigon (1) , Manon Barthe (1) , Ines Metatla (2) , Kevin Rogers (2) , Ida Chiara Guerrera (2) , Franck Chiappini (3) , Agnes Choppin (3) Pulmonary fibrosis is a progressive lung disease characterized by scarring and stiffening of lung tissue, ultimately leading to [...]
News | Non classé
Nous sommes ravis de présenter, à l'occasion du congrès ESTIV 2024 à Prague, un poster et une présentation orale sur notre projet MAT-PL (ANR-MAT-PL/ANR-22-CE18-0013), en collaboration avec PKDERM, sur "SUCCESSFUL GENERATION OF THREE-DIMENSIONAL HUMAN PRECISION-CUT LUNG SLICES FOR PULMONARY FIBROSIS MODELING". ESTIV_00118[74]
Media Publications
Yacine Khelif, Jérôme Toutain, Marie-Sophie Quittet, Sandrine Chantepie, Xavier Laffray , Samuel Valable, Didier Divoux , Fernando Sineriz, Emanuelle Pascolo-Rebouillat, Dulce Papy-Garcia, Denis Barritault, Omar Touzani, Myriam Bernaudin Abstract Alteration of the extracellular matrix (ECM) is one of the major events in the pathogenesis of brain lesions following ischemic stroke. [...]
Media Publications
P Mestries, C Alexakis, D Papy-Garcia, A Duchesnay, D Barritault, J P Caruelle, P Kern Abstract Regenerating agents (RGTA) are defined as heparan sulfate mimics, which in vivo stimulate tissue repair. RGTA are obtained by controlled grafting of carboxymethyl and sulfate groups on dextran polymers. RGTA are selected in vitro, [...]
Media Publications
Miao Tong, Bastiaan Tuk, Peng Shang, Ineke M Hekking, Esther M G Fijneman, Marnix Guijt, Steven E R Hovius, Johan W van Neck Abstract Wound healing in diabetes is frequently impaired, and its treatment remains a challenge. We tested a therapeutic strategy of potentiating intrinsic tissue regeneration by restoring the [...]
Media Publications
Denis Barritault, Marie Gilbert-Sirieix, Kim Lee Rice, Fernando Siñeriz, Dulce Papy-Garcia, Christophe Baudouin, Pascal Desgranges, Gilbert Zakine, Jean-Louis Saffar, Johan van Neck Abstract The importance of extracellular matrix (ECM) integrity in maintaining normal tissue function is highlighted by numerous pathologies and situations of acute and chronic injury associated with dysregulation [...]
CLERAPLIQ | DERMAPLIQ
Clerapliq -RGTA® or ReGeneraTing Agents mimic heparan sulfate in regenerative medicine: from concept to curing patients Denis Barritault & Marie Gilbert-Sirieix & Kim Lee Rice & Fernando Siñeriz & Dulce Papy-Garcia & Christophe Baudouin & Pascal Desgranges & Gilbert Zakine & Jean-Louis Saffar8 & Johan van Neck Abstract The [...]
DERMAPLIQ
Dermapliq - Regenerating matrix-based therapy for chronic wound healing Suzanne L Groah, Alexander Libin, Miriam Spungen, Kim-Loan Nguyen, Earthaleen Woods, Marjan Nabili, Jessica Ramella-Roman, Denis Barritault The aim of this study was to determine whether a skin-specific bioengineered regenerating agent (RGTA) heparan sulphate mimetic (CACIPLIQ20) improves chronic wound healing. [...]