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Laurie Perdigon (1) , Manon Barthe (1) , Hanan Osman-Ponchet (1) , Agnes Choppin (2) , Franck Chiappini (2) Human precision-cut lung slices (hPCLS) are a promising ex vivo model for respiratory research. These thin, precisely-cut tissues, obtained from fresh lungs using a vibrating microtome, retain the native 3D architecture [...]
6 November 2024
Manon Barthe (1) , Laurie Perdigon (1) , Hanan Osman-Ponchet (1) , Agnès Choppin (2) , Franck Chiapini (2) Pulmonary fibrosis is a progressive, restrictive lung disease characterized by scarring and stiffening of lung tissue, ultimately leading to respiratory failure. This condition is driven by the excessive proliferation and migration [...]
6 November 2024
Ahmed M Bata, Katarzyna J Witkowska, Piotr A Wozniak, Klemens Fondi, Gerald Schmidinger, Niklas Pircher, Stephan Szegedi, Valentin Aranha Dos Santos, Anca Pantalon, René M Werkmeister, Gerhard Garhofer, Leopold Schmetterer, Doreen Schmidl Abstract Importance: Corneal abrasions are frequent after standard (epithelium-off [epi-off]) corneal collagen cross-linking (CXL) in patients with progressive [...]
31 May 2022
P Desgranges, C Barbaud, J P Caruelle, D Barritault, J Gautron Abstract schemia and denervation of EDL muscle of adult rat induce a large central zone of degeneration surrounded by a thin zone of peripheral surviving muscle fibers. Muscle regeneration is a complex phenomenon in which many agents interact, such [...]
31 May 2022
Q Escartin, C Lallam-Laroye, B Baroukh, F O Morvan, J P Caruelle, G Godeau, D Barritault, J L Saffar Abstract Periodontitis are diseases of the supportive tissues of the teeth provoked by bacteria and characterized by gingival inflammation and bone destruction. We have developed a new strategy to repair tissues [...]
31 May 2022
Yacine Khelif, Jérôme Toutain, Marie-Sophie Quittet, Sandrine Chantepie, Xavier Laffray , Samuel Valable, Didier Divoux , Fernando Sineriz, Emanuelle Pascolo-Rebouillat, Dulce Papy-Garcia, Denis Barritault, Omar Touzani, Myriam Bernaudin Abstract Alteration of the extracellular matrix (ECM) is one of the major events in the pathogenesis of brain lesions following ischemic stroke. [...]
31 May 2022
P Mestries, C Alexakis, D Papy-Garcia, A Duchesnay, D Barritault, J P Caruelle, P Kern Abstract Regenerating agents (RGTA) are defined as heparan sulfate mimics, which in vivo stimulate tissue repair. RGTA are obtained by controlled grafting of carboxymethyl and sulfate groups on dextran polymers. RGTA are selected in vitro, [...]
27 May 2022
Miao Tong, Bastiaan Tuk, Peng Shang, Ineke M Hekking, Esther M G Fijneman, Marnix Guijt, Steven E R Hovius, Johan W van Neck Abstract Wound healing in diabetes is frequently impaired, and its treatment remains a challenge. We tested a therapeutic strategy of potentiating intrinsic tissue regeneration by restoring the [...]
27 May 2022
